Endocrine Abstracts

Purpose: Diabetes is one of the most common metabolic disease which has got many peptide hormones have in its etiology. Phoenixin (PNX), a recently discovered neuropeptide appears to have a role in energy management and metabolism through regulating insulin neogenesis and secretion, according to research. There is no research has been studied on the association between diabetes and PNX levels. The aim of the study was to see if there was a relation between PNX levels in the se...

Introduction: Acromegaly is a clinical syndrome associated with excess growth hormone. The present study aimed to investigate sarcopenia and frailty, which could affect mortality and morbidity, in patients with acromegaly.Method: Twenty outpatients diagnosed with acromegaly were included in the study. The hand muscle strength of the patients was measured by electronic hand dynamometer (Model EH101, Zhongshan Camry Electronic Co. Ltd. China). Computed tom...

Introduction: Pancreatitis is one of the serious side effects of glucagon-like peptide-1 receptor analog exenatide, which is an incretin hormone with anti-glycemic effects secreted from the intestine and is used for treating type 2 diabetes.Case: A 60-year-old female patient with type 2 diabetes mellitus for 11 years had been using exenatide for 6 years (no history of acute pancreatitis) along with insulin glargine and metformin. She was admitted to the ...

Introduction: Vitamin D is a fat soluble prohormone and can be produced in the body with adequate sunlight exposure or taken up by consumed foods or supplements. Recently vitamin D deficiency has been seen in pandemic. A rare disease, vitamin D intoxication is usually iatrogenic. High levels of 25(OH) vitamin D increases the intestinal calcium absorption and causes severe and refractory hypercalcemia. In this case report we presented a patient with pancreatitis and hypercalcem...

Introduction: Diabetes mellitus (DM) is a metabolic illness caused by insulin resistance or lack of it. Hypertension (HT) has been seen frequently in diabetic patients, and causes morbidity and mortality with its complications. Salusins are vasodilator and hypotensive peptids which function most in cardiovascular system. Apelin is an insulin-sensitive, vasoconstructive, positive inotropic-effective peptide. In this study, determining the levels of serum salusin-α, salusin...

Introduction: Diabetes mellitus is an important public health problem due to defects of the effect of the insulin or insulin deficiency, accompanied by chronic microvascular complications with diabetic nephropathy is characterised by proteinuria that the increasing number of patients progress to end stage renal disease. Many peptide hormone made in etiopathogenesis is situated, although adropin which discovered in recent years involves in glucose homeostasis, its relation to d...

Background/purpose: The combination of DM and HT accelerates vascular complications and increases the risk of mortality and morbidity. Hypertension is seen in half of diabetic patients. HT can be detected in approximately 40% of newly diagnosed diabetic patients. DM frequency increased 2.5 times in hypertensive patients. The association of HT and DM is due to the common mechanism responsible for the pathogenesis of both diseases. There is a limited number of studies investigat...

Introduction: Diabetes mellitus is a metabolic disease which causes acute and chronic complications including insulin deficiency and ineffectiveness or both its incidence is increasing every day. Urinary tract infections are more frequently seen and can lead a more aggressive course in diabetic patients when compared with the population in general. The aim of this study is to determine antibacterial susceptibilities of Gram-negative bacteria isolated from diabetic and non-diab...

Objective: Nonalcoholic steatohepatitis (NASH) is a metabolic disease characterized by liver steatosis. There is a correlation between liver steatosis and metabolic hormone dysregulation. Subfatin and asprosin are two important metabolic components of adipose tissue and play a role in carbohydrate metabolism, insulin resistance, and glucose regulation. Therefore, the primary aims of this study were to determine how serum and salivary subfatin and asprosin levels change simulta...

IntroductionThe prevalence and mortality of the new type of coronavirus (SARS Cov-2) are high in patients with metabolic disease, especially in diabetes circumstances. Therefore, this study aims to present the changes in the clinical and biochemical parameters of a patient with Type 1 diabetes who died due to Covid-19.Case Table 1. Laborat...